- Title
- Predicting attrition of men with a history of violence from randomised clinical trials
- Creator
- Doring, Natalie; Hwang, Ye In; Akpanekpo, Emaediong; Gullotta, Mathew; Ton, Bianca; Knight, Lee; Knight, Crosbi; Schofield, Peter; Butler, Tony Gerard
- Relation
- Trials Vol. 24, Issue 1, no. 740
- Publisher Link
- http://dx.doi.org/10.1186/s13063-023-07774-3
- Publisher
- BioMed Central
- Resource Type
- journal article
- Date
- 2023
- Description
- Preventing dropout (attrition) from clinical trials is vital for improving study validity. Dropout is particularly important in justice-involved populations as they can be very challenging to engage and recruit in the first instance. This study identifies factors associated with dropout in a double-blind, placebo-controlled randomised control trial of a selective serotonin reuptake inhibitor (SSRI) aimed at reducing reoffending in highly impulsive men with histories of violent offending. Age, education, social support, psychiatric history, and length of previous incarceration were identified as factors that predict attrition. These findings are consistent with previous research examining variables associated with attrition in clinical trials for community and offender populations. We also explored referral source and treatment allocation as attrition predictors. Although neither significantly predicted attrition, we identified that there are discernible differences in the median time to attrition among the referral source subgroups. Understanding factors that predict treatment completion and attrition will allow researchers to identify participants for whom additional provisions may optimise retention and inform development of targeted interventions.
- Subject
- attrition; retention; randomised clinical trials; treatment attrition; offender intervention; dropout; SDG 16; Sustainable Development Goals
- Identifier
- http://hdl.handle.net/1959.13/1496599
- Identifier
- uon:54189
- Identifier
- ISSN:1745-6215
- Language
- eng
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